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Abstract #2682

Development of an optimized approach to spinal cord fMRI based on the combination of an ad hoc acquisition method and data analysis pipeline

Michela Fratini1, Marta Moraschi2, Laura Maugeri1, Silvia Tommasin3, Mauro DiNuzzo2, Julien Cohen-Adad4, Fabio Mangini5, Daniele Mascali6, and Federico Giove2
1CNR-Nanotec, rome, Italy, 2Centro Ricerche Enrico Fermi, Rome, Italy, 3Sapienza University of Rome, Rome, Italy, 4Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada, 5Santa Lucia Foundation, Rome, Italy, 6Centro Ricerche Enrico Fermi, rome, Italy

The spinal cord (SC) is the caudal extension of the Central Nervous System (CNS) and is responsible for several complex functions. Among imaging methods, functional Magnetic Resonance Imaging (fMRI) represents the most promising tool for non-invasive investigation of SC functions/dysfunctions. However, the utilization of SC-fMRI is widely under-exploited, either due to challenges in acquiring good quality data, or to the lack of dedicated analysis tools. In this study, we implemented an optimized experimental approach and defined a pipeline for SC-fMRI data analysis. We validate such pipeline and investigate the impact of acquisition direction on noise removal.

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