Phase-based denoising methods in BOLD fMRI can remove signal contributions from large draining veins. Here, we investigate the performance of this methodology in a covert sentence production task, where part of the activations observed in the inferior frontal gyrus (e.g. Broca’s region) may reflect macrovascular effects from large perisylvian veins. We found significant signal denoising at the left pars orbitalis, a region in Broca’s area which is located next to the Sylvian fissure that thus contains macrovascular veins. Our results demonstrate that this method is efficient to remove undesired signal contributions and improve the spatial specificity of brain activation maps.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords