In a preliminary evaluation of task-based motor fMRI data of five healthy subjects, locally low-rank (LLR) denoising is evaluated for clinical performance. Complex-valued timecourse echo planar imaging (EPI) data from finger-tapping exams were LLR-denoised and equivalently processed alongside control images. Statistical thresholds of LLR-denoised and control data were assessed by four board-certified neuroradiologists for four specific clinically relevant clusters and overall. LLR denoising predominantly yields increased thresholds for four specific cluster regions and aggregate maps in a preliminary analysis.
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