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Abstract #2761

T1 and T2 mapping for Monitoring Liver Regeneration in Normal and Cirrhotic Liver Rats after Partial Hepatectomy

Qiu caixin1, Xie shuangshuang1, Sun yajie1, Zhu jinxia2, Xu yahui1, and Shen wen1
1Radiology Department, Tianjin First Center Hospital, TIANJIN, China, 2MR Collaboration, Siemens Healthcare Ltd., BEIJING, China

In this study, we used T1 and T2 mapping to quantify the microscopic changes of residual liver in normal and cirrhotic liver rats after partial hepatectomy (PH). The results showed that liver regeneration activity was more active in the rats with 70% PH than 30% PH, consistent with changes in T1 and T2 values. Furthermore, regeneration in cirrhotic liver was slower than in normal liver. However, in the process of regeneration, liver cirrhosis may be reversed to different degrees. The results suggested that T1 and T2 mapping can be used to assess liver regeneration after PH.

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