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Abstract #2893

Non-contrast, high spatial resolution coronary magnetic resonance angiography versus coronary computed tomography angiography

Reza Hajhosseiny1, Imran Rashid1, Aurélien Bustin1, Camila Munoz1, Gastao Cruz1, Muhummad Sohaib Nazir1, Karine Grigoryan1, Tevfik F. Ismail1, Rebecca Preston2, Radhouene Neji1,3, Karl Kunze1,3, Reza Razavi1, Amedeo Chiribiri1, Pier Giorgio Masci1, Ronak Rajani1, Claudia Prieto1, and René M. Botnar1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Department of Radiology, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom, 3MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Conventional coronary magnetic resonance angiography (CMRA) is limited by long and unpredictable acquisition-times, low spatial resolution and motion related image quality degradation. To overcome these challenges, we have proposed a highly undersampled acquisition with image-based navigators and non-rigid motion correction to enable high resolution (0.9mm3) CMRA with ≈11min acquisition time. In 30 patients with suspected coronary artery disease (CAD) who also underwent a coronary computed tomography angiography (CCTA), our CMRA framework achieved excellent image quality across all coronary artery segments, with a per patient sensitivity of 100%, specificity of 68% and negative predictive value of 100% for identifying/excluding significant CAD.

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