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Abstract #2905

Visualizing Human Aortic Valve Opening and Closing with Sub-Millisecond Temporal Resolution Over a Reduced Field-of-View

Zheng Zhong1,2, Qingfei Luo1, Kaibao Sun1, Guangyu Dan1,2, Muge Karaman1,2, and Xiaohong Joe Zhou1,2,3,4
1CMRR, University of Illinois at Chicago, Chicago, IL, United States, 2Bioengineering, University of Illinois at Chicago, Chicago, IL, United States, 3Neurosurgery, University of Illinois at Chicago, Chicago, IL, United States, 4Radiology, University of Illinois at Chicago, Chicago, IL, United States

An imaging technique, coined epi-based Sub-millisecond Periodic Event Encoded Dynamic Imaging, or epi-SPEEDI, has been shown capable of visualizing the rapid opening and closing of human aortic valve with sub-millisecond temporal resolution. However, the acquisition time of epi-SPEEDI was relatively long (8-10 breath holds). Herein, we report an alternative SPEEDI technique with a reduced FOV, which we call rFOV-SPEEDI, to shorten the scan times. This technique has been successfully applied to visualization of human aortic valve opening and closing with a temporal resolution of 0.6 ms, together with a scan time reduction of 32.5%.

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