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Abstract #2925

Extra low dose pancuronium bromide for fMRI improves survival and recovery times while suppressing translational motion 

Muhammad Danial Afiq Bin Abdullah1, Isaac Huen1, Redha Boubertakh1, Xing Qi Teo1, and Kuan Jin Lee1
1SBIC, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore

Minimising motion artefacts for pre-clinical studies requires the use of pancuronium bromide (PB), a muscle relaxant paired with the use of mechanical ventilators. Current literature is limited in its description of the mice recovery from the effects of PB. We detail a recovery process using low dose PB which improves survival while keeping translational motion suppressed.

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