Meeting Banner
Abstract #2954

Examining short-term longitudinal and activity-based variability of femoral cartilage T2 relaxation times in healthy subjects

Lauren Watkins1,2, Andrew Schmidt1, Elka Rubin1, Marco Barbieri1, Arjun Desai1,3, Valentina Mazzoli1, Marianne Black1, Garry Gold1,2, Brian Hargreaves1,2,3, Akshay Chaudhari1,4, and Feliks Kogan1
1Radiology, Stanford University, Stanford, CA, United States, 2Bioengineering, Stanford University, Stanford, CA, United States, 3Electrical Engineering, Stanford University, Stanford, CA, United States, 4Biomedical Data Science, Stanford University, Stanford, CA, United States

Subtle variations in T2 relaxation times may be related to the risk of early osteoarthritis and progression. It is important to estimate T2 variability in healthy individuals as a basis for cross-sectional and longitudinal comparisons. We examine short-term T2 variability in femoral articular cartilage of healthy volunteers over 5 days and 5 weeks and consider the impacts of physical activity. Over both periods, mean T2 change, variance, and CVRMS were small and comparable between knees and cartilage subregions. There was a moderate positive correlation between T2 changes and weekly rated perceived exertion over 5 weeks

This abstract and the presentation materials are available to members only; a login is required.

Join Here