This study aimed to quantitative measurements of the cartilage volume , thickness and T2 relaxation times in patients with symptomatic mild to moderate KOA by using T2 mapping in 3 T MR. The prototypic software were used to evaluate 17 mild KOA and 14 moderate KOA patients. Both biochemical imaging and morphologic examinations were sensitive to study the mild to moderate KOA. Compared with the mild, the moderate OA patients exhibited decreased CV and CT with the growth of K-L grade, and the T2 value increased with the growth of K-L grade.
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