An efficient $$$R_{1\rho}$$$ dispersion imaging method is presented for clinical studies of the human knee cartilage at 3T. Eight constant magnetizations were prepared by tailoring both duration and amplitude of a fully-refocused spin-lock preparation pulse. The limited initial magnetization dynamic range was expanded by the measure from the magic angle location in the deep femoral cartilage. The proposed method was applied to four asymptomatic knees from three subjects. The results from repeated scans and from comparisons with the literature indicate that the proposed method is a promising tool to further explore $$$R_{1\rho}$$$ dispersion of human knee cartilage in clinical settings.
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