Abstract #2981

T1 and T1rho Relaxation in Equine Groove Model of Cartilage Damage

Olli Nykänen¹, Nina E Hänninen^1,2, Swetha Pala¹, Ali Mohammadi¹, Mohammadhossein Ebrahimi^1,2, Nikae CR te Moller³, Harold Brommer³, Rene van Weeren³, Janne TA Mäkelä¹, Rami K Korhonen¹, Juha Töyräs^1,4,5, and Mikko J Nissi^1,2

¹Department of Applied Physics, University of Eastern Finland, Kuopio, Finland, ²Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, ³Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands, ⁴Diagnostic Imaging Center, Kuopio University Hospital, Kuopio, Finland, ⁵School of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, Australia

In this study, we examined the T1 and T1rho relaxation times of surgically damaged articular cartilage of equine carpal joints. Two different damage models (sharp and blunt grooves), inducing variation into the type of cartilage damage, were examined. The study revealed that adiabatic T1rho relaxation time is significantly increased in the bluntly damaged cartilage when compared to control cartilage. No significant differences between different damage models or between sharply damaged and control groups were seen for either T1 or T1rho relaxation. Moreover, both relaxation times correlated moderately (R≈0.65) with equilibrium modulus of articular cartilage.

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