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Abstract #3052

Fast-Sweep Frequency-Modulated SSFP: Boosting Sensitivity for 3D Joint T1/T2 Mapping

Volkert Roeloffs1, Nick Scholand1,2, and Martin Uecker1,2,3
1Institute for Diagnostic and Interventional Radiology, University Medical Center Göttingen, Goettingen, Germany, 2DZHK (German Centre for Cardiovascular Research), Partner Site Göttingen, Germany, Goettingen, Germany, 3Campus Institute Data Science (CIDAS), University of Göttingen, Göttingen, Germany, Goettingen, Germany

Sensitivity to T1 and T2 in frequency-modulated SSFP sequences can be increased by choosing a higher modulation speed without prolonging the repetition time. In this work, we assess the boost in sensitivity by Cramér-Rao-bound analysis, combine the sequence with stack-of-stars sampling and subspace-constrained reconstruction, and demonstrate joint T1/T2/B1/off-resonance mapping in phantom and in vivo study. The results render fast-sweep frequency-modulated SSFP an excellent candidate for comprehensive 3D multi-parametric mapping.

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