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Abstract #3055

Optimization of fast Quantitative Multiparameter Mapping (MPM) at 7T using parallel transmission

Difei Wang1, Rüdiger Stirnberg1, Eberhard Pracht1, and Tony Stöcker1,2
1German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany, 2Department of Physics and Astronomy, University of Bonn, Bonn, Germany

We propose a fast MPM protocol at 7T using skipped-CAIPI 3D-EPI with simple PTx water-excitation based on 3 kT-points. By comparison to corresponding CP mode scans, the 3 kT-points excitation mainly improves the B1+ field homogeneity in the Cerebellum. Using MPM B1+ field correction, this simple improvement is sufficient to achieve good and homogeneous T1, PD and T2* estimates throughout the brain. However, the lack of MT homogenization still results in the inadequate MTsat CNR. By combining MPM with EPI and PTx, we obtained quantitative whole-brain parameter maps of high quality, except for Cerebellar MTsat within 3 minutes scan time.

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