Zero TE (ZTE) sequences have been demonstrated to be capable of achieving CT-like images of the skull and C-spine. To obtain high-resolution images of the skull and c-spine, two separate acquisitions are often performed. Although in general cortical bone, soft tissue and air could be differentiated based on the signal intensity, fatty tissues and connective tissues can be problematic due to the chemical shift artifacts and/or having similar signals to that of cortical bones. This work demonstrated that with optimized protocol and advanced post-processing, ZTE MRI allows for high quality skull and C-spine images in a single acquisition.
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