A new evaluating system based on tumor immunohistochemistry and preoperative MRI features in spinal giant cell tumor of bone to predicting overall survival of total en bloc spondylectomy patients with over 2 years follow up. The largest lesion diameter (>4.2 cm) and the vertebral compression were independent predictors of postoperative recurrence. According to Kaplan-Meier survival analysis, the cystic change in the lesion and the degree of compression ≥50% suggest a worse clinical outcome. The expression levels of vascular endothelial growth factor and p53 gene have no obvious clinical significance on the survival outcome. H3F3A was positively expressed in our cohort.
This abstract and the presentation materials are available to members only; a login is required.