Ultrashort echo time magnetization transfer (UTE-MT) sequence can quantify magnetization transfer ratio (MTR) values of short T2 tissues, which has potential to evaluate early disc degeneration. The current study aims to assess the feasibility of UTE-MT quantification of cartilaginous endplate for evaluation of early disc degeneration. In addition, the latent associations between the UTE-MTR and grade of disc degeneration, age, gender, the oswestry disability index (ODI) were evaluated, respectively. Our results demonstrated that the UTE-MT sequence is feasible to quantify cartilaginous endplate in lumbar spine. UTE-MTR may be a potentially useful biomarker in the assessment of early lumbar disc degeneration.