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Abstract #3199

Histogram analysis of IDEAL-IQ and UTE images better assists to detect abnormalities of the lumbar vertebral bone marrow in patients with different stages of chronic kidney disease

Yan Xiong1, Weiyin Vivian Liu 2, Fan He1, Yanan Wang1, Yao Zhang1, Shuang Hu1, and Xiaoming Li1
1Wuhan Tongji Hospital, Wuhan, China, 2MR Research, GE Healthcare, Beijing, China

Mineral bone disease (MBD) has an extremely high incidence in patients with chronic kidney disease (CKD) and significantly affects the prognosis and quality of life of patients. However, the current diagnostic methods are difficult to determine the type and severity of CKD-MBD. In our study, histogram analysis of IDEAL-IQ showed kurtosis and R2* could distinguish bone marrow changes in patients with CKD at different stages in indication of altered skeletal health and bi-component analysis of UTE images demonstrated short T2* value possibly in reflection of trabecular bone was highly correlated with blood biochemical indicators.

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