Turbo spin-echo based T2 quantification of neoplasms is affected by partial volume effects resulting in underestimation of T2 values leading to lesion misclassification. Bi-exponential models proposed for two-component T2 estimation do not account for flip angle variations across the excited slice due to RF imperfections. This work presents a two-component model for accurate T2 estimation in the presence of partial volume which considers the slice profile of the excitation and refocusing pulses. The proposed model has <4% relative error in slices affected by partial volume and allows good separation between benign and malignant lesions in the abdomen.
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