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Abstract #3309

Fat-insensitive T2water measurement using multiple Dixon turbo spin-echo acquisitions with effective echo time increments

Ruaridh M Gollifer1,2, Tim JP Bray1,3, Margaret Hall-Craggs1,3, and Alan Bainbridge2
1Centre for Medical Imaging (CMI), University College London, London, United Kingdom, 2Department of Medical Physics and Bioengineering, University College London Hospital, London, United Kingdom, 3Department of Imaging, University College London Hospital, London, United Kingdom

Short tau inversion recovery (STIR) imaging is the mainstay of clinical imaging in inflammatory musculoskeletal (MSK) diseases, and generates hyperintense signal in areas of inflammation in bone marrow (bone marrow oedema). However, the assessment of STIR images of bone marrow is based on qualitative judgement of signal intensity and can be confounded by variations in fat content resulting from the healing response in bone to inflammation. We aimed to develop a method which would (1) separate fat and water and (2) provide a water-specific T2 measurement, enabling separation and individual quantification of oedema and fat in the bone marrow.

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