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Abstract #3324

Distinction of T2 quantitative measurements between the nucleus pulposus and anulus fibrosus using Gaussian-fitted histogram analysis

Xiaoqing Liang1, Weiyin Vivian Liu2, Jingyi Wang1, and Xiaoming Li1
1Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2MR Research,GE Healthcare, Beijing, China

The distinction between the nucleus pulposus (NP) and the peripheral annulus fibrosus (AF) of intervertebral disc is an important diagnostic indicators of intervertebral disc degeneration (IVDD) on MRI. So far, there have not been many studies or mature approaches to quantify the distinction between the NP and AF. This study aimed to discover histogram distribution of the T2 relaxation time of the AF and NP using Gaussian fitting. Our results showed that Gaussian-fitted histogram analysis of T2 relaxation time could achieve quantitative distinction between the NP and AF, and computed Gaussian-fitted histogram parameters had good performance on diagnosing IVDD.

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