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Abstract #3372

Multi-centre, multi-vendor 7 Tesla fMRI reproducibility of hand digit representation in the human somatosensory cortex

Ian D Driver1, Rosa M Sanchez Panchuelo2, Olivier Mougin2, Michael Asghar2, James Kolasinski1, William T Clarke3, Catarina Rua4, Andrew T Morgan5, Adrian Carpenter4, Keith Muir5, David Porter5, Christopher T Rodgers4, Stuart Clare3, Richard G Wise1,6,7, Richard Bowtell2, and Susan T Francis2
1Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, United Kingdom, 2Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 3Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, United Kingdom, 4Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom, 5Imaging Centre of Excellence, University of Glasgow, Glasgow, United Kingdom, 6Department of Neuroscience, Imaging and Clinical Sciences, "G. D’Annunzio University" of Chieti-Pescara, Chieti, Italy, 7Institute for Advanced Biomedical Technologies, "G. D’Annunzio University" of Chieti-Pescara, Chieti, Italy

This study compares within- and across-site reproducibility of 7 Tesla somatomotor fMRI using a travelling wave task to map the hand and individual digit localization at high spatial resolution. We performed a “travelling-heads” study acquiring data on Siemens Magnetom, Siemens Terra and Philips Achieva whole-body 7 Tesla MRI systems at five sites. Simple harmonization of the EPI sequence protocol was performed. We show metrics of intra- and inter-site variability of digit representations, with good reproducibility observed across sites. These results demonstrate the potential benefits of multi-site 7T fMRI studies for digit mapping where large cohorts are required.

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