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Abstract #3470

Investigating layer specific MR properties in the superior colliculus ex vivo at 14.1T 

Ju Young Lee1, Andreas Mack2, Thomas Shiozawa-Bayer2, Marc Himmelbach3, Gisela Hagberg1,4, and Klaus Scheffler1,4
1Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 2Eberhard Karls University Tuebingen, Tübingen, Germany, 3Hertie-Institue for Clinical Brain Research, Tübingen, Germany, 4University Hospital Tübingen, Tübingen, Germany

Layer specific MR properties have previously been observed in the superior colliculus in vivo at 9.4T. The present study investigates layer specific MR properties in R2* and R1 in more detail in post mortem brain stem samples at 14.1T. Similar to in vivo, one R2* maximum that likely corresponds to the superficial optic layer (layer III) was observed. Ex vivo we could observe high R2* and R1 in an area likely corresponding to the deep white layer (layer VII) of the superior colliculus. In the R1maps, this area showed a strong contrast towards the periaqueductal gray.

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