Morphological analysis of the spinal cord can provide valuable insight into injury and degeneration of damaged cord tissues. Accurate morphological analysis requires high resolution 3D anatomic imaging to be utilized as inputs into automated or semi-automated post-processing analysis algorithms. Historically, high resolution 3D imaging of the instrumented spinal cord has been difficult to achieve. As a result, the substantial damage and pathology near hardware cannot be analyzed using advanced morphological tools. In this technical feasibility study, isotropic 3D-MSI metal-artifact suppressed images are collected and utilized within a novel analysis framework constructed around the Spinal Cord Toolbox infrastructure.
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