Abstract #3541

Accurate mUlti-echo phase image wiTh uneven echO spacing and Ultra-High Dynamic Range (AUTO-HDR)

Yuheng Huang^1,2, Xinheng Zhang^1,2, Serry Fradad¹, Lu Meng¹, Ghazal Yoosefian¹, Linda Azab¹, Xinqi Li³, Alan Kwan⁴, Rohan Dharmakumar¹, Hui Han¹, and Hsin-Jung Yang¹

¹Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States, ²Bioengineering, UCLA, Los Angeles, CA, United States, ³Columbia University, New York, NY, United States, ⁴Cardiology, Cedars Sinai Medical Center, Los Angeles, CA, United States

A strong off-resonance field around metallic implants induces unreliable phase maps and limits the application of phase-based MRI techniques. State-of-the-art MR phase mapping and unwrapping techniques perform poorly under the influence of metallic implants because of their limited dynamic range and susceptibility to noise. In this study, we developed a fully automatic phase mapping technique based on a multi-echo GRE sequence with unevenly spaced echoes and a high-dynamic-range phase reconstruction algorithm. We tested the proposed method with numerical simulations and human subjects with metallic implants.

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