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Abstract #3541

Accurate mUlti-echo phase image wiTh uneven echO spacing and Ultra-High Dynamic Range (AUTO-HDR)

Yuheng Huang1,2, Xinheng Zhang1,2, Serry Fradad1, Lu Meng1, Ghazal Yoosefian1, Linda Azab1, Xinqi Li3, Alan Kwan4, Rohan Dharmakumar1, Hui Han1, and Hsin-Jung Yang1
1Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States, 2Bioengineering, UCLA, Los Angeles, CA, United States, 3Columbia University, New York, NY, United States, 4Cardiology, Cedars Sinai Medical Center, Los Angeles, CA, United States

A strong off-resonance field around metallic implants induces unreliable phase maps and limits the application of phase-based MRI techniques. State-of-the-art MR phase mapping and unwrapping techniques perform poorly under the influence of metallic implants because of their limited dynamic range and susceptibility to noise. In this study, we developed a fully automatic phase mapping technique based on a multi-echo GRE sequence with unevenly spaced echoes and a high-dynamic-range phase reconstruction algorithm. We tested the proposed method with numerical simulations and human subjects with metallic implants.

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