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Abstract #3572

Performance of XTC imaging in a free-breathing mouse model exploring variable saturation delay timesĀ 

Tahmina Susan Achekzai1, Luis Loza2, Stephen Kadlecek2, Kai Ruppert2, Faraz Amzajerdian2, and Rahim R. Rizi1
1Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2University of Pennsylvania, Philadelphia, PA, United States

XTC imaging takes advantage of the exchange between gas and dissolved phase Xe to provide information on lung function, as direct dissolved phase imaging is limited in signal. In this study, we demonstrate XTC imaging in a regular and transgenic mouse model. We aim to optimize depolarization effectiveness by varying delay time and number of saturation pulses applied in the imaging scheme and demonstrate the dependence of depolarization to these parameters.

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