Abstract #3582

Off-Resonance Correction with Self-Estimated Field Map for Hyperpolarized 13C Metabolic Imaging

Xiaoxi Liu¹, Shuyu Tang^1,2, Xucheng Zhu^1,3, and Peder E.Z. Larson¹

¹Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, ²HeartVista, Inc., Los Altos, CA, United States, ³GE Healthcare, Sunnyvale, CA, United States

Hyperpolarized ¹³C magnetic resonance imaging is a non-invasive imaging tool to assess metabolic process in-vivo that has been most commonly applied to imaging cancer and heart disease. Spiral readout, as a rapid acquisition technique, is commonly used to acquire hyperpolarized metabolic data. However, the spiral readout is sensitive to the off-resonance effect and has blurring artifacts as a result. The blurring also affects the measurement of metabolism. In this project, we investigated two off-resonance correction methods with self-estimated field maps and applied them on different anatomies.

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