Parametric techniques like native T1 and T2 mapping showed a strong positive correlation with T2* in the non-invasive assessment of cardiac iron overload. T1 mapping was shown to be superior to T2 mapping in the diagnosis of cardiac iron overload. 30% of the study population had normal T2* values, but low T1 values. T1 mapping may be more sensitive in the detection of patients with early/mild cardiac iron overload, who are being missed by T2*.
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