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Abstract #3617

Time-averaged wall shear stress: a potential indicator for carotid intra-plaque hemorrhage

Rui Shen1, Huiyu Qiao1, Zihan Ning1, Dongye Li2, Dandan Yang1, and Xihai Zhao1
1Center for Biomedical Imaging Research, Tsinghua University, Beijing, China, 2Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China

We investigated the relationship between the TAWSS and presence of plaque components in histology combined with plaque burden metrics interpreted from multi-contrast MR images among patients scheduled for CEA within one week. Based on 18 patients with 60-slice histological and MR images, correlation analysis revealed that there is an association between the presence of IPH and TAWSS. In addition, our findings indicated that TAWSS can improve the performance of plaque burden metrics, MWT in predicting presence of IPH.

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