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Abstract #3679

Functional evaluation of placenta with fetal growth restriction based on mDixon-Quant imaging

Jie Li1, Xiao Ling1, Tao Wen1, Rui Wang1, Zhongping Zhang2, Kai Ai3, and Jing Zhang1
1Lanzhou University second hospital, Lanzhou, China, 2Philips Healthcare, Guangzhou, China, 3Philips Healthcare, Xi'an, China

Estimating placental function is highly desirable, as impaired placental function is associated with FGR and poor neonatal outcome. This study evaluated variations of T2* after oxygen inhalation of 8 pregnant women in the second and third trimesters using quantitative mDixon-Quant imaging. The hyperoxic T2* after oxygen inhalation was significantly higher than baseline T2* which defined as before oxygen inhalation. The change of baseline T2* and hyperoxic T2* was significantly negative correlated with gestational age. The result showed that |△T2*| was correlated with placental function. We speculate T2* based mDixon-Quant imaging is useful in noninvasive assessment of placental function.

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