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Abstract #3681

Predictive Ki-67 proliferation index of cervical squamous cell carcinoma based on IVIM-DWI combined with texture features

Cuiping Li1 and Jiangning Dong2
1Radiology Department, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science, Hefei, China, 2The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China

As the most common histological type in cervical cancer, cervical squamous cell carcinoma (CSCC) mainly affects young women, and most of whom are diagnosed between 35-50 years old. In recent years, studies on tumor biomarkers have continuously increased, Ki-67 was considered as a kind of nuclear protein related to cell proliferation, some previous studies have shown that Ki-67 proliferation index (PI) is positively correlated with tumor size, invasion, cancer stage and patient survival. In our study work, we investigated the prediction of Ki-67 PI through combining intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI) with texture analysis (TA) for CSCC patients.

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