A four-dimensional (4D) numerical phantom, which is defined by the three-dimensional (3D) spatial axes and the resonance frequency axis, is indispensable for Bloch simulations of protons in biological tissues with complex distribution of materials. In this study, a 4D phantom was created using an image dataset of an actual biological sample containing water and fat, and the Bloch simulation was performed using the phantom. As a result, 3D images of the samples containing water and fat were successfully reproduced, which demonstrated the usefulness of the concept of the proposed 4D phantom.
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