Diffusion Kurtosis Imaging (DKI) estimates non-Gaussian diffusion in biological tissue from diffusion-weighted MRI, providing a useful marker for individual differences in tissue microstructure. We present a well-tested, well-documented open-source implementation of DKI as part of the DIPY (Diffusion Imaging in Python) project. The implementation provides standard DKI metrics, as well as extensions of the method for microstructure modeling and tractography. We demonstrate the use of these methods in openly available datasets.
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