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Abstract #3779

Evidence for tissue dielectric property differences between neonates and adults: a retrospective study using MR-EPT

Roy Kurtzbard1, Anthony Price2, Joseph V Hajnal1,2, Jeffrey W Hand2, and Shaihan J Malik1,2
1Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Electromagnetic simulations for RF safety calculation require knowledge of tissue dielectric properties, but these are not well understood for neonates whose tissues have much higher water content than adults. This work retrospectively used MR-EPT on archived raw data obtained from a study on 800+ neonates, to measure tissue conductivity and permittivity at 128MHz. Presented are initial results from 50 subjects. The measured properties are rather noisy at the individual level, but across the whole cohort the median brain conductivity in neonates is approximately 1.8 times greater than in adults, in line with expectations from scaling arguments.

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