Abstract #3808

Setup of a cryogen-free DNP polarizer in a preclinical imaging lab

Arianna Ferrari¹, Josh Philipp Peters¹, Mariia Anikeeva¹, Frowin Ellermann¹, Andrey Pravdivtsev¹, Kolja Them¹, and Jan-Bernd Hövener^1,2

¹SBMI Rad. UKSH, Kiel, Germany, ²Emmy Noether Group Molecular and Metabolic MRI - M3, Freiburg, Germany

The setup of a cryogen-free device for dissolution dynamic nuclear polarization (dDNP) in an imaging facility is described. Fully automated procedures were used to calibrate the system and to perform hyperpolarization of pyruvic acid. Polarizations exceeding 30 % were achieved routinely within an experiment duration of less than an hour. Pitfalls are discussed and solutions proposed.

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