Abstract #3883

Multi-parametric functional and structural assessment of the placenta at late gestational ages using MRI

Daphna Link¹, Netanell Avisdris^1,2, Xingfeng Shao³, Liat Ben-Sira^4,5, Leo Joskowicz², Ilan Gull⁶, Danny J.J Wang³, and Dafna Ben-Bashat^1,5

¹Sagol Brain Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ²School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel, ³Laboratory of FMRI Technology (LOFT), USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, ⁴Division of Pediatric Radiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁵Sackler Faculty of Medicine & Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel, ⁶Ultrasound Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

Early and accurate placental insufficiency assessment is of a great importance. Here we comprehensively assessed placental perfusion and structure, and fetal brain and body volumes, in normal fetuses and in cases with fetal growth restriction (FGR) caused by placental insufficiency, at late gestational ages (GA=31-34 weeks). Increased Placental Blood Flow and Arterial Transit Time were detected in normal cases compared to earlier GA reported previously. Significant differences were found in several placental and fetal characteristics between normal and FGR cases. This study emphasizes the importance of multi-parametric assessment of fetuses to enable identification of high risks for FGR.

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