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Abstract #3918

Development of MR Elastography Methods for Assessing Adhesion Between Pituitary Masses and the Optic Chiasm

Yi Sui1, Myung-Ho In1, Salomon Cohen-Cohen2, Erin Gray1, Kevin Glaser1, Matt A. Bernstein1, Jamie J Van Gompel2, Richard L. Ehman1, John Huston III1, and Ziying Yin1
1Radiology, Mayo Clinic, Rochester, MN, United States, 2Neurologic Surgery, Mayo Clinic, Rochester, MN, United States

Preoperatively knowing if a pituitary adenoma is adhering to the optic chiasm would help to predict the risk of surgically induced vision loss. MR-elastography based slip interface imaging has been successfully developed to predict tumor adhesion using normalized octahedral shear strain (NOSS). This pilot study demonstrates the feasibility of acquiring NOSS at ~1mm high resolution using a newly developed distortion-free EPI-MRE technique on a high-performance compact 3T system. With further development, this technique will have great potential to identify adhesion between pituitary adenomas with the adjacent optic chiasm.

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