Delayed post-gadolinium FLAIR can delineate peri- and endo-lymphatic spaces to capture endolymphatic hydrops, the pathological counterpart of Ménière’s disease. However, the four hours delay between injection and acquisition is a burden for patients and staff. No previous work has proposed a satisfying delineation of inner ear internal anatomy without injection yet. This study presents step-by-step 3D-FLAIR optimizations with specific T2 preparation and inversion time to maximize the contrast between peri- and endo-lymphatic spaces. We showed that optimized 3D-FLAIR sequence allowed delineating saccule and utricle in healthy volunteers without injection, paving the way toward future application to diagnose Meniere disease.
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