IRIS (Image Reconstruction using Image-space Sampling Function) is a DWI sequence for Multi shot (Mhs) echo planar imaging (EPI) with phase correction. The purpose of this study is to investigate the usefulness of IRIS for optic nerve, in which SSh EPI-DWI tends to show poor image quality due to magnetic susceptibility artifacts. As a result of comparing image quality among Single shot (SSh) EPI-DWI, SSh turbo spin echo (TSE)-DWI, MSh TSE-DWI, and IRIS, IRIS was the best sequence to visualize the optic nerve. IRIS suppressed magnetic susceptibility artifacts most clearly, and can provide excellent contrast with high robustness.
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