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Abstract #3943

Prognostic value of quantitative dynamic contrast-enhanced magnetic resonance imaging and texture analysis for nasopharyngeal carcinoma

Yuhui Qin1,2, Xiaoping Yu2, Jing Hou2, and Fabao Gao1
1Department of Radiology, West China Hospital, Chengdu, China, 2Department of Radiology, Affiliated Cancer Hospital of Xiangya School of Medicine, Changsha, China

Although several studies have demonstrated that DCE-MRI is helpful in predicting the short-term therapeutic response for NPC, the relationship between the quantitative parameters and texture features (based on DCE-MRI and T2WI) and the prognosis of NPC is unclear. The present work is the first study to explore the performance of quantitative DCE-MRI and texture analysis in predicting the long-term outcome of NPC. Our data revealed that baseline quantitative DCE-MRI parameters and texture features might serve as predictors for the prognosis of NPC. These findings provide new insights to help optimize individual treatment regimen and improve the clinical outcome for patients.

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