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Abstract #3958

Multi-scale Accelerated Auto-differentiable Bloch-simulation based joint design of excitation RF and gradient waveforms.

Tianrui Luo1, Douglas C. Noll1, Jeffrey A. Fessler1, and Jon-Fredrik Nielsen1
1University of Michigan, Ann Arbor, MI, United States

A recently proposed auto-differentiable Bloch simulation approach allows joint design of RF and gradient waveforms for large-tip objectives. However, that approach requires a relatively long design time, preventing online pulse design. As a refinement, we propose to accelerate such simulation-based pulse design approaches by dividing it into two stages: 1) fast coarse dwell time design; 2) fine dwell time tuning. This combination substantially reduced the design time (from 8.5 min to 3 min), while still attaining high excitation accuracy, enabling online pulse design applications.

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