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Abstract #4082

Diffusion MRI of THAs for the Classification of Synovial Reactions

Madeleine A. Gao1, Ek T. Tan1, John Neri1, Bin Lin1, Alissa J. Burge1, Hollis G. Potter1, Kevin M. Koch2, and Matthew F. Koff1
1Radiology and Imaging, Hospital of Special Surgery, New York, NY, United States, 2Medical College of Wisconsin, Milwaukee, WI, United States

The classification of synovial reactions caused by adverse local tissue reactions or prosthetic joint infections in total hip arthroplasty patients has remained a challenge due to the in-plane and through-plane distortions caused by metallic components. MAVRIC-based diffusion weighted imaging (DWI) is an innovative MRI technique sensitive to microstructural fluid changes and utilizes apparent diffusion coefficient values for the differentiation of diseased and non-diseased tissues. This study evaluated the effectiveness of MAVRIC-based DWI and T2 mapping in differentiating between types of synovial reactions. Our DWI ADC biomarker showed promise in differentiating between normal and abnormal synovial reaction subtypes within THA patients.

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