High b value DWI (b2000) shows insufficient image contrast between benign and malignant tissues and much overlap between ADCs of low grade and those of high-grade prostate cancers (PCs). Forty-nine patients with PC underwent multiparametric MRI including ultra-high b value DWI (b3000) and high b value DWI. Signal intensity of normal prostate was significantly lower in b3000 than in b2000. Other image quality parameters, tumor detection ability, and discrimination ability of PC aggressiveness between b3000 and b2000 were comparable. Compared with high b value DWI, ultra-high b value DWI could not contribute to increased diagnostic performance in PC.
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