Recently, prostate disease prevalence has been shown to increase gradually. Amide proton transfer-weighted (APTw) imaging, a molecular MRI technique at the protein level, has been applied in the diagnosis of prostate disease. This study aims to explore the optimal scan parameters for prostate APTw MR imaging. The preliminary results showed higher SNR of APTw images in central zones was acquired with the optimal scan parameters including the echo train length, the numbers and thickness of slices, FOV, the type of fold-over suppression and shimming, the size of voxel and phase encoding direction.
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