While lesion-symptom mapping can inform on which brain regions are crucial for a given behavior, it is still unclear whether different lesion etiologies show comparable structure-function relationships. In this study, support-vector regression lesion-symptom maps were compared between a glioma and stroke population. As expected, pathology distinct coverage patterns in the brain were found and there were more and larger significant voxel clusters in the tumor group. Our preliminary conclusion is that despite some differences in lesion-symptom associations in comparing a tumor and stroke population, these two populations can provide complementary information regarding involvement of brain regions for given cognitive tasks.
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