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Abstract #4167

T2 Quantification in Brain Using Three Dimensional Fast Spin Echo Imaging with Long Echo Trains

Jeff Snyder1 and Alan H Wilman1
1Biomedical Engineering, University of Alberta, Edmonton, AB, Canada

A 3D FSE method using variable flip angle trains is proposed for quantification of T2 in brain. Two images are acquired at different echo times to allow for decay curve fitting using Bloch equation and Echo Phase Graph (EPG) simulations. Echo train lengths of 96 and 192 were investigated (total scan times of 8:12 and 2:38) in phantom and healthy subjects at 3 T, with isotropic resolutions of 0.9 and 1.3 mm3, respectively. RF was optimized to reduce blurring, sustain signal and allow T2 resolution. Comparison with previous methods was excellent, with good resolution and contrast in the 96 case.

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