In this work, a highly accelerated 3D EPI prototype sequence implementation and scanner in-line reconstruction are introduced. The proposed sequence provides a flexible combination of single-/multi-shot schemes, in-plane segmentation, image resolution, echo-train length, partial Fourier factors, 2D-CAIPIRINHA/2D-GRAPPA-based acceleration, and CAIPIRINHA shift. Initial tests presented herein indicate suitability for highly accelerated high-resolution susceptibility-based imaging with significantly reduced scan time, such as whole-head coverage at 0.65 mm isotropic resolution within 2 minutes.
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