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Abstract #4198

Analytical Characterization and Comparison of Magnetization-Relaxation-Induced Point Spread Functions of TFE, bSSFP and TSE Acquisitions

Dan Zhu1 and Qin Qin2,3
1Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States, 2The Division of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States, 3F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States

Fast image acquisition is commonly used in quantitative MRI after contrast preparation, such as turbo-filed-echo (TFE), balance steady-state-free-precession (bSSFP), and turbo-spin-echo (TSE). k-Space data acquired are filtered by a modulation transfer function (MTF), causing contrast loss and blurring. Here, we derived the analytical formulation of the corresponding point spread function (PSF) of Cartesian TFE, bSSFP and TSE with 180° refocusing. The contrast-to-noise ratio (CNR) is defined and maximized, providing an analytically optimized selection of TFE/TSE factors and flip angles. bSSFP serves high CNR, small FWHM and large TFE factors. Long TR and short TE are suggested for TFE studies.

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