Abstract #4203

MIXTURE: A novel sequence for simultaneous morphological and quantitative imaging based on multi-interleaved 3D turbo-spin echo MRI

Masami Yoneyama¹, Takayuki Sakai², Shuo Zhang³, Daichi Murayama², Hajime Yokota⁴, Yansong Zhao⁵, Shinji Saruya⁶, Masashi Suzuki⁶, Atsuya Watanabe^7,8, Mamoru Niitsu⁶, and Marc Van Cauteren⁹

¹Philips Japan, Tokyo, Japan, ²Department of Radiology, Eastern Chiba Medical Center, Chiba, Japan, ³Philips Healthcare, Hamburg, Germany, ⁴Department of Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan, ⁵Philips Healthcare, Cleveland, OH, United States, ⁶Department of Radiology, Saitama Medical University, Saitama, Japan, ⁷Department of Orthopaedic Surgery, Eastern Chiba Medical Center, Chiba, Japan, ⁸General Medical Services, Graduate School of Medicine, Chiba University, Chiba, Japan, ⁹Philips Healthcare, Best, Netherlands

3D high-resolution magnetic resonance imaging (MRI) is clinically essential for an accurate assessment of subtle pathophysiological changes in different anatomies. However, long exam time remains a practical challenge that requires additional scans for either complementary quantitative parametric mapping or morphological information for clinical diagnosis. In this study, we introduce a novel method termed Multi-Interleaved X-prepared TSE with inTUitive RElaxometry (MIXTURE) for simultaneous morphological and quantitative imaging with volumetric isotropic resolution within one single scan and demonstrate the approach in multi-contrast quantitative knee imaging with direct T2- or T1ρ-mapping.

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