Abstract #4205

Lumbar Fatty Acid Composition (FAC) Measurement in Osteoporosis Patients Using MRI

Lina Lin¹, Lutian Bai¹, Qun Cheng², Manuel Schneider³, Marcel Dominik Nickel³, Caixia Fu⁴, Guangwu Lin¹, and Shihong Li¹

¹Department of Radiology, Huadong Hospital, Fudan University, Shanghai, China, ²Department of Osteoporosis, Huadong Hospital, Fudan University, Shanghai, China, ³MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, ⁴Application Development, Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China

This study is to explore the application value of fatty acid composition (FAC) measurements in the diagnosis of osteoporosis. 39 subjects who underwent dual-energy X-ray absorptiometry (DXA) and lumbar magnetic resonance imaging on a 3T scanner were included. We found that FF value was negatively correlated with T value (P < 0.05, r = -0.371), and SF value was positively correlated with T value (P < 0.05, r = 0.399). The PUF value of the osteopenia group was significantly higher than that of the osteoporosis group（P < 0.05）and normal bone mass group（P < 0.05）.

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