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Abstract #4244

Towards Catheter-based Intra-Arterial Spin Labeling for Perfusion Measurements

Kevin Waescher1, Simon Reiss1, Ali Caglar Özen1,2, Thomas Lottner1, and Michael Bock1
1Dept. of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 2German Consortium for Translational Cancer Research Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany

MR-guided catheterization with injection of Gd-based contrast agent allows for quantitative perfusion measurement of the myocardium in coronary interventions. However, Gd is contraindicated in patients with impaired renal function, and it changes the relaxation times in the target organ after injection, so that a characterization of the target tissue becomes difficult. In this study, we provide a different solution to quantify perfusion using arterial spin labelling with a catheter based coil. The results show that ASL using a local catheter based labelling coil provides an alternative technique for perfusion measurements during cardiovascular interventions without exogenous contrast agents.

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